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» Progestins breast cancer

Study Suggests Progestin, Not Estrogen, Is the Real Cancer Culprit in Hormone Replacement Therapy

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Progestins and What are

This finding is consistent with in vivo data suggesting that progesterone does not have a detrimental effect on breast tissue. These progestins also oppose the increase in IGFBP-1 caused by oral estrogens, and this effect probably contributes to the increase in IGF-I activity reviewed in [ ]. Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals. Bitner said treatment must be tailored to the individual. Continuous-combined regimen inhibits the sloughing of mammary epithelium that occurs after progesterone withdrawal in a cyclic regimen. USA [ 13 ] case-control, cases 1.

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